1L7T

Crystal Structure Analysis of the anti-testosterone Fab fragment

Summary for 1L7T

• Entry DOI: 10.2210/pdb1l7t/pdb
• Related: 1L7S
• Descriptor: anti-testosterone (light chain), anti-testosterone (heavy chain) (3 entities in total)
• Functional Keywords: anti-testosterone, fab fragment, affinity and specificity matured, immune system
• Biological source: Mus musculus (house mouse); More
• Cellular location: Cell membrane ; Single-pass membrane protein : P01869
• Total number of polymer chains: 2
• Total formula weight: 47735.61

Authors

Valjakka, J.,Hemminki, A.,Niemi, S.,Soderlund, H.,Takkinen, K.,Rouvinen, J. (deposition date: 2002-03-17, release date: 2002-10-02, Last modification date: 2018-04-04)

• Primary citation: Valjakka, J.,Hemminki, A.,Niemi, S.,Soderlund, H.,Takkinen, K.,Rouvinen, J.; Crystal Structure of an in Vitro Affinity- and Specificity-matured Anti-testosterone Fab in Complex with Testosterone. IMPROVED AFFINITY RESULTS FROM SMALL STRUCTURAL CHANGES WITHIN THE VARIABLE DOMAINS; J.Biol.Chem., 277:44021-44027, 2002; PubMed: 12196551; DOI: 10.1074/jbc.M208392200

Experimental method

X-RAY DIFFRACTION (2.1 Å)