1KWR
HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH INHIBITOR 0134-36
Summary for 1KWR
Entry DOI | 10.2210/pdb1kwr/pdb |
Related | 1KWQ |
Descriptor | Carbonic anhydrase II, ZINC ION, 1-METHYL-3-OXO-1,3-DIHYDRO-BENZO[C]ISOTHIAZOLE-5-SULFONIC ACID AMIDE, ... (4 entities in total) |
Functional Keywords | lyase, zinc, inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm : P00918 |
Total number of polymer chains | 1 |
Total formula weight | 29598.76 |
Authors | Grueneberg, S.,Stubbs, M.T. (deposition date: 2002-01-30, release date: 2003-01-07, Last modification date: 2024-02-14) |
Primary citation | Gruneberg, S.,Stubbs, M.T.,Klebe, G. Successful virtual screening for novel inhibitors of human carbonic anhydrase: strategy and experimental confirmation. J.Med.Chem., 45:3588-3602, 2002 Cited by PubMed: 12166932DOI: 10.1021/jm011112j PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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