1KV5
Structure of Trypanosoma brucei brucei TIM with the salt-bridge-forming residue Arg191 mutated to Ser
Summary for 1KV5
Entry DOI | 10.2210/pdb1kv5/pdb |
Descriptor | triosephosphate isomerase, glycosomal, 2-PHOSPHOGLYCOLIC ACID, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ... (6 entities in total) |
Functional Keywords | tim barrel, mutant, salt bridge, isomerase |
Biological source | Trypanosoma brucei brucei |
Cellular location | Glycosome: P04789 |
Total number of polymer chains | 2 |
Total formula weight | 54522.19 |
Authors | Kursula, I.,Partanen, S.,Lambeir, A.-M.,Wierenga, R.K. (deposition date: 2002-01-25, release date: 2002-03-29, Last modification date: 2023-08-16) |
Primary citation | Kursula, I.,Partanen, S.,Lambeir, A.-M.,Wierenga, R.K. The importance of the conserved Arg191-Asp227 salt bridge of triosephosphate isomerase for folding, stability, and catalysis FEBS Lett., 518:39-42, 2002 Cited by PubMed: 11997014DOI: 10.1016/S0014-5793(02)02639-X PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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