1K3B
Crystal Structure of Human Dipeptidyl Peptidase I (Cathepsin C): Exclusion Domain Added to an Endopeptidase Framework Creates the Machine for Activation of Granular Serine Proteases
Summary for 1K3B
Entry DOI | 10.2210/pdb1k3b/pdb |
Descriptor | dipeptydil-peptidase I exclusion domain, dipeptydil-peptidase I light chain, dipeptydil-peptidase I heavy chain, ... (7 entities in total) |
Functional Keywords | hydrolase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 40120.33 |
Authors | Turk, D.,Janjic, V.,Stern, I.,Podobnik, M.,Lamba, D.,Dahl, S.W.,Lauritzen, C.,Pedersen, J.,Turk, V.,Turk, B. (deposition date: 2001-10-02, release date: 2002-04-02, Last modification date: 2020-07-29) |
Primary citation | Turk, D.,Janjic, V.,Stern, I.,Podobnik, M.,Lamba, D.,Dahl, S.W.,Lauritzen, C.,Pedersen, J.,Turk, V.,Turk, B. Structure of human dipeptidyl peptidase I (cathepsin C): exclusion domain added to an endopeptidase framework creates the machine for activation of granular serine proteases. EMBO J., 20:6570-6582, 2001 Cited by PubMed: 11726493DOI: 10.1093/emboj/20.23.6570 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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