1JXJ

Role of mobile loop in the mechanism of human salivary amylase

Summary for 1JXJ

• Entry DOI: 10.2210/pdb1jxj/pdb
• Related: 1JXK 1SMD
• Descriptor: Alpha-amylase, salivary, CALCIUM ION, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: amylase, mutagenesis, catalysis, human, salivary, enzyme, mobile loop, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 55957.73

Authors

Ramasubbu, N.,Ragunath, C.,Wang, Z.,Mishra, P.J.,Thomas, L.M. (deposition date: 2001-09-07, release date: 2001-09-14, Last modification date: 2023-08-16)

• Primary citation: Ramasubbu, N.,Ragunath, C.,Mishra, P.J.,Thomas, L.M.,Kandra, L.; Human salivary alpha-amylase Trp58 situated at subsite -2 is critical for enzyme activity.; Eur.J.Biochem., 271:2517-2529, 2004; PubMed: 15182367; DOI: 10.1111/j.1432-1033.2004.04182.x

Experimental method

X-RAY DIFFRACTION (1.99 Å)