1JWP
Structure of M182T mutant of TEM-1 beta-lactamase
Summary for 1JWP
Entry DOI | 10.2210/pdb1jwp/pdb |
Descriptor | BETA-LACTAMASE TEM, PHOSPHATE ION (3 entities in total) |
Functional Keywords | protein stability, tem-1, beta-lactamase, antibiotic resistance, evolution, hydrolase |
Biological source | Escherichia coli |
Total number of polymer chains | 1 |
Total formula weight | 29006.88 |
Authors | Wang, X.,Minasov, G.,Shoichet, B.K. (deposition date: 2001-09-04, release date: 2002-06-05, Last modification date: 2023-08-16) |
Primary citation | Wang, X.,Minasov, G.,Shoichet, B.K. Evolution of an antibiotic resistance enzyme constrained by stability and activity trade-offs. J.Mol.Biol., 320:85-95, 2002 Cited by PubMed: 12079336DOI: 10.1016/S0022-2836(02)00400-X PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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