1JPA

Crystal Structure of unphosphorylated EphB2 receptor tyrosine kinase and juxtamembrane region

Summary for 1JPA

Entry DOI	10.2210/pdb1jpa/pdb
Descriptor	neural kinase, Nuk=Eph/Elk/Eck family receptor-like tyrosine kinase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER (3 entities in total)
Functional Keywords	receptor tyrosine kinase, autoinhibited, unphosphorylated, juxtamembrane, transferase
Biological source	Mus musculus (house mouse)
Cellular location	Membrane; Single-pass type I membrane protein: P54763
Total number of polymer chains	2
Total formula weight	71661.32
Authors	Wybenga-Groot, L.E.,Pawson, T.,Sicheri, F. (deposition date: 2001-08-01, release date: 2001-10-03, Last modification date: 2024-04-03)
Primary citation	Wybenga-Groot, L.E.,Baskin, B.,Ong, S.H.,Tong, J.,Pawson, T.,Sicheri, F. Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase by the unphosphorylated juxtamembrane region. Cell(Cambridge,Mass.), 106:745-757, 2001 Cited by PubMed: 11572780 DOI: 10.1016/S0092-8674(01)00496-2 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.91 Å)

Structure validation