1JO1
N7-Guanine Adduct of 2,7-diaminomitosene with DNA
Summary for 1JO1
Entry DOI | 10.2210/pdb1jo1/pdb |
Descriptor | 5'-D(*GP*TP*GP*(DAJ)GP*TP*AP*TP*AP*CP*CP*AP*C)-3', DECARBAMOYL-2,7-DIAMINOMITOSENE (2 entities in total) |
Functional Keywords | double helix, major groove binding drug, guanine-n7-alkylator, dna |
Total number of polymer chains | 2 |
Total formula weight | 7817.38 |
Authors | Subramaniam, G.,Paz, M.M.,Kumar, G.S.,Das, A.,Palom, Y.,Clement, C.C.,Patel, D.J.,Tomasz, M. (deposition date: 2001-07-26, release date: 2001-09-12, Last modification date: 2024-05-22) |
Primary citation | Subramaniam, G.,Paz, M.M.,Suresh Kumar, G.,Das, A.,Palom, Y.,Clement, C.C.,Patel, D.J.,Tomasz, M. Solution structure of a guanine-N7-linked complex of the mitomycin C metabolite 2,7-diaminomitosene and DNA. Basis of sequence selectivity. Biochemistry, 40:10473-10484, 2001 Cited by PubMed: 11523988DOI: 10.1021/bi010965a PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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