1ICF
CRYSTAL STRUCTURE OF MHC CLASS II ASSOCIATED P41 II FRAGMENT IN COMPLEX WITH CATHEPSIN L
Summary for 1ICF
Entry DOI | 10.2210/pdb1icf/pdb |
Descriptor | PROTEIN (CATHEPSIN L: HEAVY CHAIN), PROTEIN (CATHEPSIN L: LIGHT CHAIN), PROTEIN (INVARIANT CHAIN), ... (5 entities in total) |
Functional Keywords | cysteine proteinase, cathepsin, mhc class ii, invariant chain, thyroglobulin type-1 domain, hydrolase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 62721.42 |
Authors | Guncar, G.,Pungercic, G.,Klemencic, I.,Turk, V.,Turk, D. (deposition date: 1999-01-07, release date: 2000-01-12, Last modification date: 2023-08-09) |
Primary citation | Guncar, G.,Pungercic, G.,Klemencic, I.,Turk, V.,Turk, D. Crystal structure of MHC class II-associated p41 Ii fragment bound to cathepsin L reveals the structural basis for differentiation between cathepsins L and S. EMBO J., 18:793-803, 1999 Cited by PubMed: 10022822DOI: 10.1093/emboj/18.4.793 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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