1I8I
CRYSTAL STRUCTURE OF DSFV MR1 IN COMPLEX WITH THE PEPTIDE ANTIGEN OF THE MUTANT EPIDERMAL GROWTH FACTOR RECEPTOR, EGFRVIII, AT ROOM TEMPERATURE
Summary for 1I8I
Entry DOI | 10.2210/pdb1i8i/pdb |
Related | 1i8k |
Descriptor | EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY MR1SCFV LIGHT CHAIN, EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY MR1SCFV HEAVY CHAIN, EPIDERMAL GROWTH FACTOR RECEPTOR, EGFRVIII PEPTIDE ANTIGEN, ... (4 entities in total) |
Functional Keywords | antibody-peptide complex, immunoglobulin fold, peptide antigen, type ii' beta turn, immune system |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 3 |
Total formula weight | 26878.92 |
Authors | Landry, R.C.,Klimowicz, A.C.,Lavictoire, S.J.,Borisova, S.,Kottachchi, D.T.,Lorimer, I.A.,Evans, S.V. (deposition date: 2001-03-14, release date: 2002-03-14, Last modification date: 2021-10-27) |
Primary citation | Landry, R.C.,Klimowicz, A.C.,Lavictoire, S.J.,Borisova, S.,Kottachchi, D.T.,Lorimer, I.A.,Evans, S.V. Antibody recognition of a conformational epitope in a peptide antigen: Fv-peptide complex of an antibody fragment specific for the mutant EGF receptor, EGFRvIII. J.Mol.Biol., 308:883-893, 2001 Cited by PubMed: 11352579DOI: 10.1006/jmbi.2001.4628 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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