1I48

CYSTATHIONINE GAMMA-SYNTHASE IN COMPLEX WITH THE INHIBITOR CTCPO

Summary for 1I48

Entry DOI	10.2210/pdb1i48/pdb
Related	1qgn
Descriptor	CYSTATHIONINE GAMMA-SYNTHASE, PYRIDOXAL-5'-PHOSPHATE, CARBOXYMETHYLTHIO-3-(3-CHLOROPHENYL)-1,2,4-OXADIAZOL (3 entities in total)
Functional Keywords	plp-dependent enzyme, homotetramer, inhibitor complex, ctcpo, lyase
Biological source	Nicotiana tabacum (common tobacco)
Total number of polymer chains	12
Total formula weight	583029.68
Authors	Steegborn, C.,Laber, B.,Messerschmidt, A.,Huber, R.,Clausen, T. (deposition date: 2001-02-20, release date: 2001-09-05, Last modification date: 2023-08-09)
Primary citation	Steegborn, C.,Laber, B.,Messerschmidt, A.,Huber, R.,Clausen, T. Crystal structures of cystathionine gamma-synthase inhibitor complexes rationalize the increased affinity of a novel inhibitor. J.Mol.Biol., 311:789-801, 2001 Cited by PubMed: 11518531 DOI: 10.1006/jmbi.2001.4880 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.25 Å)

Structure validation