1I1F
Crystal structure of human class i mhc (hla-a2.1) complexed with beta 2-microglobulin and hiv-rt variant peptide i1y
Summary for 1I1F
Entry DOI | 10.2210/pdb1i1f/pdb |
Descriptor | PROTEIN (CLASS I HISTOCOMPATIBILITY ANTIGEN, GOGO-A0201 ALPHA CHAIN), PROTEIN (BETA 2-MICROGLOBULIN), PROTEIN (HIV-RT VARIANT PEPTIDE I1F (FLKEPVHGV)) (3 entities in total) |
Functional Keywords | human class i mhc, hiv, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P01892 Secreted: P61769 |
Total number of polymer chains | 6 |
Total formula weight | 89521.55 |
Authors | Kirksey, T.J.,Pogue-Caley, R.R.,Frelinger, J.A.,Collins, E.J. (deposition date: 1999-04-16, release date: 2000-01-12, Last modification date: 2023-08-09) |
Primary citation | Kirksey, T.J.,Pogue-Caley, R.R.,Frelinger, J.A.,Collins, E.J. The structural basis for the increased immunogenicity of two HIV-reverse transcriptase peptide variant/class I major histocompatibility complexes. J.Biol.Chem., 274:37259-37264, 1999 Cited by PubMed: 10601290DOI: 10.1074/jbc.274.52.37259 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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