1I00
CRYSTAL STRUCTURE OF HUMAN THYMIDYLATE SYNTHASE, TERNARY COMPLEX WITH DUMP AND TOMUDEX
Summary for 1I00
Entry DOI | 10.2210/pdb1i00/pdb |
Related | 1HZW |
Descriptor | THYMIDYLATE SYNTHASE, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, TOMUDEX, ... (4 entities in total) |
Functional Keywords | thymidylate synthase, human, ternary complex, dump, tomudex, open conformation, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: P04818 |
Total number of polymer chains | 2 |
Total formula weight | 67911.48 |
Authors | Almog, R.A.,Waddling, C.A.,Maley, F.,Maley, G.F.,Van Roey, P. (deposition date: 2001-01-27, release date: 2001-05-09, Last modification date: 2023-08-09) |
Primary citation | Almog, R.,Waddling, C.A.,Maley, F.,Maley, G.F.,Van Roey, P. Crystal structure of a deletion mutant of human thymidylate synthase Delta (7-29) and its ternary complex with Tomudex and dUMP. Protein Sci., 10:988-996, 2001 Cited by PubMed: 11316879DOI: 10.1110/ps.47601 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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