1HYO
CRYSTAL STRUCTURE OF FUMARYLACETOACETATE HYDROLASE COMPLEXED WITH 4-(HYDROXYMETHYLPHOSPHINOYL)-3-OXO-BUTANOIC ACID
Summary for 1HYO
Entry DOI | 10.2210/pdb1hyo/pdb |
Related | 1QCN 1QCO 1QQJ |
Descriptor | FUMARYLACETOACETATE HYDROLASE, MAGNESIUM ION, CALCIUM ION, ... (7 entities in total) |
Functional Keywords | beta-sandwich roll, hydrolase |
Biological source | Mus musculus (house mouse) |
Total number of polymer chains | 2 |
Total formula weight | 93259.06 |
Authors | Bateman, R.L.,Bhanumoorthy, P.,Witte, J.F.,McClard, R.W.,Grompe, M.,Timm, D.E. (deposition date: 2001-01-21, release date: 2001-02-14, Last modification date: 2023-08-09) |
Primary citation | Bateman, R.L.,Bhanumoorthy, P.,Witte, J.F.,McClard, R.W.,Grompe, M.,Timm, D.E. Mechanistic inferences from the crystal structure of fumarylacetoacetate hydrolase with a bound phosphorus-based inhibitor. J.Biol.Chem., 276:15284-15291, 2001 Cited by PubMed: 11154690DOI: 10.1074/jbc.M007621200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.3 Å) |
Structure validation
Download full validation report