1HJF
Alteration of the co-substrate selectivity of deacetoxycephalosporin C synthase: The role of arginine-258
Summary for 1HJF
Entry DOI | 10.2210/pdb1hjf/pdb |
Related | 1DCS 1E5H 1E5I 1HJG 1RXF 1RXG |
Descriptor | DEACETOXYCEPHALOSPORIN C SYNTHASE, FE (II) ION, 2-OXO-4-METHYLPENTANOIC ACID, ... (4 entities in total) |
Functional Keywords | oxidoreductase, alternative 2-oxoacids, cephem antibiotic biosynthesis, chemical cosubstrate rescue, co-substrate selectivity, 2- oxoglutarate-dependent oxygenase |
Biological source | STREPTOMYCES CLAVULIGERUS |
Total number of polymer chains | 1 |
Total formula weight | 34748.56 |
Authors | Lee, H.J.,Lloyd, M.D.,Clifton, I.J.,Harlos, K.,Dubus, A.,Baldwin, J.E.,Frere, J.M.,Schofield, C.J. (deposition date: 2001-01-15, release date: 2001-06-01, Last modification date: 2023-12-13) |
Primary citation | Lee, H.J.,Lloyd, M.D.,Harlos, K.,Clifton, I.J.,Baldwin, J.E.,Schofield, C.J. Alteration of the 2-Oxoacid Cosubstrate Selectivity in Deacetoxycephalosporin C Synthase: The Role of Arginine-258 J.Biol.Chem., 276:18290-, 2001 Cited by PubMed: 11279000DOI: 10.1074/JBC.M100085200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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