1GYP
CRYSTAL STRUCTURE OF GLYCOSOMAL GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE FROM LEISHMANIA MEXICANA: IMPLICATIONS FOR STRUCTURE-BASED DRUG DESIGN AND A NEW POSITION FOR THE INORGANIC PHOSPHATE BINDING SITE
Summary for 1GYP
Entry DOI | 10.2210/pdb1gyp/pdb |
Descriptor | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, PHOSPHATE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (3 entities in total) |
Functional Keywords | oxidoreductase (aldehyde(d)-nad+(a)) |
Biological source | Leishmania mexicana |
Cellular location | Glycosome: Q27890 |
Total number of polymer chains | 4 |
Total formula weight | 158185.98 |
Authors | Kim, H.,Feil, I.K.,Verlinde, C.L.M.J.,Petra, P.H.,Hol, W.G.J. (deposition date: 1995-08-01, release date: 1995-12-07, Last modification date: 2024-02-07) |
Primary citation | Kim, H.,Feil, I.K.,Verlinde, C.L.,Petra, P.H.,Hol, W.G. Crystal structure of glycosomal glyceraldehyde-3-phosphate dehydrogenase from Leishmania mexicana: implications for structure-based drug design and a new position for the inorganic phosphate binding site. Biochemistry, 34:14975-14986, 1995 Cited by PubMed: 7578111DOI: 10.1021/bi00046a004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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