1GYM

PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C IN COMPLEX WITH GLUCOSAMINE-(ALPHA-1-6)-MYO-INOSITOL

Summary for 1GYM

Entry DOI	10.2210/pdb1gym/pdb
Descriptor	PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C, (1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside (3 entities in total)
Functional Keywords	phosphatidylinositol specific phospholipase c, glucosaminyl (alpha-1-6)-d-myo-inositol, inhibitor complex, hydrolase (phosphoric diester), lipid degradation
Biological source	Bacillus cereus
Cellular location	Secreted: P14262
Total number of polymer chains	1
Total formula weight	34909.98
Authors	Heinz, D.W.,Ryan, M.,Smith, M.P.,Weaver, L.H.,Keana, J.F.W.,Griffith, O.H. (deposition date: 1996-05-02, release date: 1996-11-08, Last modification date: 2024-02-07)
Primary citation	Heinz, D.W.,Ryan, M.,Smith, M.P.,Weaver, L.H.,Keana, J.F.,Griffith, O.H. Crystal structure of phosphatidylinositol-specific phospholipase C from Bacillus cereus in complex with glucosaminyl(alpha 1-->6)-D-myo-inositol, an essential fragment of GPI anchors. Biochemistry, 35:9496-9504, 1996 Cited by PubMed: 8755729 DOI: 10.1021/bi9606105 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation