1GOE
Monitoring the structural Consequences of Phe12-->D-Phe12 and Leu15-->Aib15 substitution in h/r Corticotropin Releasing Hormone: Implications for Design of CRH antagonists.
Summary for 1GOE
Entry DOI | 10.2210/pdb1goe/pdb |
Descriptor | CORTICOTROPIN RELEASING HORMONE (1 entity in total) |
Functional Keywords | hormone, corticotropin releasing hormone, synthetic analogues, solid phase synthesis, solutions structure |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Secreted: P06850 |
Total number of polymer chains | 1 |
Total formula weight | 4734.44 |
Authors | Spyroulias, G.A.,Papazacharias, S.,Pairas, G.,Cordopatis, P. (deposition date: 2001-10-20, release date: 2001-10-31, Last modification date: 2015-10-21) |
Primary citation | Spyroulias, G.A.,Papazacharias, S.,Pairas, G.,Cordopatis, P. Monitoring the Structural Consequences of Phe12-->D-Phe and Leu15-->Aib Substitution in Human/Rat Corticotropin Releasing Hormone Eur.J.Biochem., 269:6009-, 2002 Cited by PubMed: 12473096DOI: 10.1046/J.1432-1033.2002.03278.X PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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