1GG8

DESIGN OF INHIBITORS OF GLYCOGEN PHOSPHORYLASE: A STUDY OF ALPHA-AND BETA-C-GLUCOSIDES AND 1-THIO-BETA-D-GLUCOSE COMPOUNDS

Summary for 1GG8

Entry DOI	10.2210/pdb1gg8/pdb
Descriptor	PROTEIN (GLYCOGEN PHOSPHORYLASE), ALPHA-D-GLUCOPYRANOSYL-2-CARBOXYLIC ACID AMIDE, PYRIDOXAL-5'-PHOSPHATE, ... (5 entities in total)
Functional Keywords	glycogen phosphorylase, inhibitor complex, catalytic site, design, transferase
Biological source	Oryctolagus cuniculus (rabbit)
Total number of polymer chains	1
Total formula weight	98093.73
Authors	Watson, K.A.,Mitchell, E.P.,Johnson, L.N.,Son, J.C.,Bichard, C.J.,Orchard, M.G.,Fleet, G.W.,Oikonomakos, N.G.,Leonidas, D.D.,Kontou, M.,Papageorgiou, A.C. (deposition date: 2000-07-30, release date: 2000-08-23, Last modification date: 2023-08-09)
Primary citation	Watson, K.A.,Mitchell, E.P.,Johnson, L.N.,Son, J.C.,Bichard, C.J.,Orchard, M.G.,Fleet, G.W.,Oikonomakos, N.G.,Leonidas, D.D.,Kontou, M.,Papageorgioui, A. Design of inhibitors of glycogen phosphorylase: a study of alpha- and beta-C-glucosides and 1-thio-beta-D-glucose compounds. Biochemistry, 33:5745-5758, 1994 Cited by PubMed: 8180201 DOI: 10.1021/bi00185a011 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.31 Å)

Structure validation