1G5M

HUMAN BCL-2, ISOFORM 1

Summary for 1G5M

Entry DOI	10.2210/pdb1g5m/pdb
Related	1BXL 1G5J 1G5O
Descriptor	PROTEIN (APOPTOSIS REGULATOR BCL-2 WITH PUTATIVE FLEXIBLE LOOP REPLACED WITH A PORTION OF APOPTOSIS REGULATOR BCL-X PROTEIN) (1 entity in total)
Functional Keywords	apoptosis
Biological source	Homo sapiens (human)
Cellular location	Mitochondrion outer membrane; Single-pass membrane protein: P10415
Total number of polymer chains	1
Total formula weight	19227.39
Authors	Petros, A.M.,Medek, A.,Nettesheim, D.G.,Kim, D.H.,Yoon, H.S.,Swift, K.,Matayoshi, E.D.,Oltersdorf, T.,Fesik, S.W. (deposition date: 2000-11-01, release date: 2001-03-21, Last modification date: 2022-12-21)
Primary citation	Petros, A.M.,Medek, A.,Nettesheim, D.G.,Kim, D.H.,Yoon, H.S.,Swift, K.,Matayoshi, E.D.,Oltersdorf, T.,Fesik, S.W. Solution structure of the antiapoptotic protein bcl-2. Proc.Natl.Acad.Sci.USA, 98:3012-3017, 2001 Cited by PubMed: 11248023 DOI: 10.1073/pnas.041619798 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation