1G5L

CO(III)-BLEOMYCIN-OOH BOUND TO AN OLIGONUCLEOTIDE CONTAINING A PHOSPHOGLYCOLATE LESION

Summary for 1G5L

• Entry DOI: 10.2210/pdb1g5l/pdb
• Related: 1G5D 1G5E 1G5K 1GIZ 1GJ0 1GJ1 1GJ2
• Descriptor: 5'-D(*CP*CP*AP*AP*AP*G)-3', 5'-D(P*AP*CP*TP*GP*GP*G)-3', 5'-D(*CP*CP*CP*AP*GP*TP*AP*CP*TP*TP*TP*GP*G)-3', ... (8 entities in total)
• Functional Keywords: damaged dna, dna-drug complex, intercalation, dna
• Total number of polymer chains: 3
• Total formula weight: 9285.54

Authors

Hoehn, S.T.,Junker, H.-D.,Bunt, R.C.,Turner, C.J.,Stubbe, J. (deposition date: 2000-11-01, release date: 2001-06-06, Last modification date: 2022-02-23)

• Primary citation: Hoehn, S.T.,Junker, H.D.,Bunt, R.C.,Turner, C.J.,Stubbe, J.; Solution structure of Co(III)-bleomycin-OOH bound to a phosphoglycolate lesion containing oligonucleotide: implications for bleomycin-induced double-strand DNA cleavage.; Biochemistry, 40:5894-5905, 2001; PubMed: 11352724; DOI: 10.1021/bi002635g

Experimental method

SOLUTION NMR