1G3N

STRUCTURE OF A P18(INK4C)-CDK6-K-CYCLIN TERNARY COMPLEX

Summary for 1G3N

• Entry DOI: 10.2210/pdb1g3n/pdb
• Related: 1BI7 1BI8
• Descriptor: CYCLIN-DEPENDENT KINASE 6, CYCLIN-DEPENDENT KINASE 6 INHIBITOR, V-CYCLIN (3 entities in total)
• Functional Keywords: cyclin-dependent kinase, ink4 inhibitor, viral cyclin, cell cycle, signaling protein
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: Q00534
• Total number of polymer chains: 6
• Total formula weight: 166461.93

Authors

Jeffrey, P.D.,Tong, L.,Pavletich, N.P. (deposition date: 2000-10-24, release date: 2001-01-10, Last modification date: 2024-02-07)

• Primary citation: Jeffrey, P.D.,Tong, L.,Pavletich, N.P.; Structural basis of inhibition of CDK-cyclin complexes by INK4 inhibitors.; Genes Dev., 14:3115-3125, 2000; PubMed: 11124804; DOI: 10.1101/gad.851100

Experimental method

X-RAY DIFFRACTION (2.9 Å)