1FYY
HPRT GENE MUTATION HOTSPOT WITH A BPDE2(10R) ADDUCT
Summary for 1FYY
Entry DOI | 10.2210/pdb1fyy/pdb |
NMR Information | BMRB: 4647 |
Descriptor | HPRT DNA WITH BENZO[A]PYRENE-ADDUCTED DA7, 5'-D(*TP*GP*CP*CP*CP*TP*TP*GP*AP*CP*TP*A)-3', 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE (3 entities in total) |
Functional Keywords | dna lesions, benzo[a]pyrene, hprt gene, diol epoxide adducts, syn-anti interconversion, dna |
Total number of polymer chains | 2 |
Total formula weight | 7629.15 |
Authors | Volk, D.E.,Rice, J.S.,Luxon, B.A.,Yeh, H.J.C.,Liang, C.,Xie, G.,Sayer, J.M.,Jerina, D.M.,Gorenstein, D.G. (deposition date: 2000-10-03, release date: 2000-12-06, Last modification date: 2024-05-22) |
Primary citation | Volk, D.E.,Rice, J.S.,Luxon, B.A.,Yeh, H.J.,Liang, C.,Xie, G.,Sayer, J.M.,Jerina, D.M.,Gorenstein, D.G. NMR evidence for syn-anti interconversion of a trans opened (10R)-dA adduct of benzo[a]pyrene (7S,8R)-diol (9R,10S)-epoxide in a DNA duplex. Biochemistry, 39:14040-14053, 2000 Cited by PubMed: 11087351DOI: 10.1021/bi001669l PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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