1FSW

AMPC BETA-LACTAMASE FROM E. COLI COMPLEXED WITH INHIBITOR CEPHALOTHINBORONIC ACID

Summary for 1FSW

• Entry DOI: 10.2210/pdb1fsw/pdb
• Related: 1C3B 1FSY 2BLS 3BLS
• Descriptor: CEPHALOSPORINASE, PHOSPHATE ION, N-2-THIOPHEN-2-YL-ACETAMIDE BORONIC ACID, ... (4 entities in total)
• Functional Keywords: cephalosporinase, beta-lactamase, serine hydrolase, hydrolase
• Biological source: Escherichia coli
• Cellular location: Periplasm: P00811
• Total number of polymer chains: 2
• Total formula weight: 79554.78

Authors

Caselli, E.,Powers, R.A.,Blaszczak, L.C.,Wu, C.Y.,Prati, F.,Shoichet, B.K. (deposition date: 2000-09-11, release date: 2001-03-14, Last modification date: 2011-07-13)

• Primary citation: Caselli, E.,Powers, R.A.,Blasczcak, L.C.,Wu, C.Y.,Prati, F.,Shoichet, B.K.; Energetic, structural, and antimicrobial analyses of beta-lactam side chain recognition by beta-lactamases.; Chem.Biol., 8:17-31, 2001; PubMed: 11182316; DOI: 10.1016/S1074-5521(00)00052-1

Experimental method

X-RAY DIFFRACTION (1.9 Å)