1FQJ
CRYSTAL STRUCTURE OF THE HETEROTRIMERIC COMPLEX OF THE RGS DOMAIN OF RGS9, THE GAMMA SUBUNIT OF PHOSPHODIESTERASE AND THE GT/I1 CHIMERA ALPHA SUBUNIT [(RGS9)-(PDEGAMMA)-(GT/I1ALPHA)-(GDP)-(ALF4-)-(MG2+)]
Summary for 1FQJ
Entry DOI | 10.2210/pdb1fqj/pdb |
Related | 1FQI 1FQK |
Descriptor | Guanine nucleotide-binding protein G(t) subunit alpha-1,Guanine nucleotide-binding protein G(i) subunit alpha-1,Guanine nucleotide-binding protein G(t) subunit alpha-1, Regulator of G-protein signaling 9, Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma, ... (7 entities in total) |
Functional Keywords | rgs9, transducin, effector, pdegamma, g protein, phototransduction, rod, rgs, phosphodiesterase, gap, signaling protein |
Biological source | Bos taurus (Bovine) More |
Cellular location | Membrane; Peripheral membrane protein: O46469 |
Total number of polymer chains | 5 |
Total formula weight | 115261.72 |
Authors | Slep, K.C.,Kercher, M.A.,He, W.,Cowan, C.W.,Wensel, T.G.,Sigler, P.B. (deposition date: 2000-09-05, release date: 2001-02-28, Last modification date: 2024-02-07) |
Primary citation | Slep, K.C.,Kercher, M.A.,He, W.,Cowan, C.W.,Wensel, T.G.,Sigler, P.B. Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 A. Nature, 409:1071-1077, 2001 Cited by PubMed: 11234020DOI: 10.1038/35059138 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.02 Å) |
Structure validation
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