1FPZ
CRYSTAL STRUCTURE ANALYSIS OF KINASE ASSOCIATED PHOSPHATASE (KAP) WITH A SUBSTITUTION OF THE CATALYTIC SITE CYSTEINE (CYS140) TO A SERINE
Summary for 1FPZ
Entry DOI | 10.2210/pdb1fpz/pdb |
Descriptor | CYCLIN-DEPENDENT KINASE INHIBITOR 3, SULFATE ION (3 entities in total) |
Functional Keywords | alpha-beta sandwich, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, perinuclear region : Q16667 |
Total number of polymer chains | 6 |
Total formula weight | 143490.72 |
Authors | Song, H.,Hanlon, N.,Brown, N.R.,Noble, M.E.M.,Johnson, L.N.,Barford, D. (deposition date: 2000-09-01, release date: 2001-05-09, Last modification date: 2024-02-07) |
Primary citation | Song, H.,Hanlon, N.,Brown, N.R.,Noble, M.E.,Johnson, L.N.,Barford, D. Phosphoprotein-protein interactions revealed by the crystal structure of kinase-associated phosphatase in complex with phosphoCDK2. Mol.Cell, 7:615-626, 2001 Cited by PubMed: 11463386DOI: 10.1016/S1097-2765(01)00208-8 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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