1FPH

THE INTERACTION OF THROMBIN WITH FIBRINOGEN: A STRUCTURAL BASIS FOR ITS SPECIFICITY

Summary for 1FPH

• Entry DOI: 10.2210/pdb1fph/pdb
• Related PRD ID: PRD_000379
• Descriptor: ALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), HIRUDIN, ... (5 entities in total)
• Functional Keywords: hydrolase, serine proteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted, extracellular space: P00734 P00734
• Total number of polymer chains: 4
• Total formula weight: 36426.90

Authors

Stubbs, M.T.,Bode, W. (deposition date: 1993-04-21, release date: 1994-01-31, Last modification date: 2012-12-12)

• Primary citation: Stubbs, M.T.,Oschkinat, H.,Mayr, I.,Huber, R.,Angliker, H.,Stone, S.R.,Bode, W.; The interaction of thrombin with fibrinogen. A structural basis for its specificity.; Eur.J.Biochem., 206:187-195, 1992; PubMed: 1587268; DOI: 10.1111/j.1432-1033.1992.tb16916.x

Experimental method

X-RAY DIFFRACTION (2.5 Å)