1FO2
CRYSTAL STRUCTURE OF HUMAN CLASS I ALPHA1,2-MANNOSIDASE IN COMPLEX WITH 1-DEOXYMANNOJIRIMYCIN
Summary for 1FO2
Entry DOI | 10.2210/pdb1fo2/pdb |
Related | 1FMI 1FO3 |
Descriptor | ALPHA1,2-MANNOSIDASE, CALCIUM ION, SULFATE ION, ... (5 entities in total) |
Functional Keywords | alpha-alpha7 barrel, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Endoplasmic reticulum membrane; Single-pass type II membrane protein: Q9UKM7 |
Total number of polymer chains | 1 |
Total formula weight | 53273.35 |
Authors | Vallee, F.,Karaveg, K.,Moremen, K.W.,Herscovics, A.,Howell, P.L. (deposition date: 2000-08-24, release date: 2001-01-17, Last modification date: 2011-07-13) |
Primary citation | Vallee, F.,Karaveg, K.,Herscovics, A.,Moremen, K.W.,Howell, P.L. Structural basis for catalysis and inhibition of N-glycan processing class I alpha 1,2-mannosidases. J.Biol.Chem., 275:41287-41298, 2000 Cited by PubMed: 10995765DOI: 10.1074/jbc.M006927200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.38 Å) |
Structure validation
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