1FEW

CRYSTAL STRUCTURE OF SMAC/DIABLO

Summary for 1FEW

• Entry DOI: 10.2210/pdb1few/pdb
• Descriptor: SECOND MITOCHONDRIA-DERIVED ACTIVATOR OF CASPASES (1 entity in total)
• Functional Keywords: smac, diablo, apoptosis, caspase activation, iap inhibition
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 20759.08

Authors

Chai, J.,Shi, Y. (deposition date: 2000-07-23, release date: 2000-09-13, Last modification date: 2024-02-07)

• Primary citation: Chai, J.,Du, C.,Wu, J.W.,Kyin, S.,Wang, X.,Shi, Y.; Structural and biochemical basis of apoptotic activation by Smac/DIABLO.; Nature, 406:855-862, 2000; PubMed: 10972280; DOI: 10.1038/35022514

Experimental method

X-RAY DIFFRACTION (2.2 Å)