1F7Z
RAT TRYPSINOGEN K15A COMPLEXED WITH BOVINE PANCREATIC TRYPSIN INHIBITOR
Summary for 1F7Z
Entry DOI | 10.2210/pdb1f7z/pdb |
Related | 1F5R 3TGI |
Descriptor | TRYPSIN II, ANIONIC, PANCREATIC TRYPSIN INHIBITOR, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | serine protease, trypsin precursor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Rattus norvegicus (Norway rat) More |
Cellular location | Secreted, extracellular space: P00763 Secreted: P00974 |
Total number of polymer chains | 2 |
Total formula weight | 32459.56 |
Authors | Pasternak, A.,White, A.,Jeffery, C.J.,Medina, N.,Cahoon, M.,Ringe, D.,Hedstrom, L. (deposition date: 2000-06-28, release date: 2001-07-04, Last modification date: 2021-11-03) |
Primary citation | Pasternak, A.,White, A.,Jeffery, C.J.,Medina, N.,Cahoon, M.,Ringe, D.,Hedstrom, L. The energetic cost of induced fit catalysis: Crystal structures of trypsinogen mutants with enhanced activity and inhibitor affinity. Protein Sci., 10:1331-1342, 2001 Cited by PubMed: 11420435DOI: 10.1110/ps.44101 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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