1F3E

A NEW TARGET FOR SHIGELLOSIS: RATIONAL DESIGN AND CRYSTALLOGRAPHIC STUDIES OF INHIBITORS OF TRNA-GUANINE TRANSGLYCOSYLASE

Summary for 1F3E

Entry DOI	10.2210/pdb1f3e/pdb
Related	1EFZ 1ENU 1PUD
Descriptor	QUEUINE TRNA-RIBOSYLTRANSFERASE, ZINC ION, 3,5-DIAMINOPHTHALHYDRAZIDE, ... (4 entities in total)
Functional Keywords	trna-modifying enzyme, glycosyltransferase, transferase
Biological source	Zymomonas mobilis
Total number of polymer chains	1
Total formula weight	43183.29
Authors	Graedler, U.,Gerber, H.-D.,Goodenough-Lashua, D.M.,Garcia, G.A.G.,Ficner, R.,Reuter, K.,Stubbs, M.T.,Klebe, G. (deposition date: 2000-06-02, release date: 2000-06-15, Last modification date: 2024-02-07)
Primary citation	Gradler, U.,Gerber, H.D.,Goodenough-Lashua, D.M.,Garcia, G.A.,Ficner, R.,Reuter, K.,Stubbs, M.T.,Klebe, G. A new target for shigellosis: rational design and crystallographic studies of inhibitors of tRNA-guanine transglycosylase. J.Mol.Biol., 306:455-467, 2001 Cited by PubMed: 11178905 DOI: 10.1006/jmbi.2000.4256 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation