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1EX0

HUMAN FACTOR XIII, MUTANT W279F ZYMOGEN

Summary for 1EX0
Entry DOI10.2210/pdb1ex0/pdb
Related1EVU
DescriptorCOAGULATION FACTOR XIII A CHAIN, CALCIUM ION, PHOSPHATE ION, ... (5 entities in total)
Functional Keywordstransglutaminase, blood coagulation, mutant, w279f, oxyanion, transferase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: P00488
Total number of polymer chains2
Total formula weight167447.60
Authors
Garzon, R.J.,Pratt, K.P.,Bishop, P.D.,Le Trong, I.,Stenkamp, R.E.,Teller, D.C. (deposition date: 2000-04-28, release date: 2003-12-23, Last modification date: 2024-02-07)
Primary citationGarzon, R.J.,Pratt, K.P.,Bishop, P.D.,Le Trong, I.,Stenkamp, R.E.,Teller, D.C.
Tryptophan 279 is Essential for the Transglutaminase Activity of Coagulation Factor XIII: Functional and Structural Characterization
To be Published,
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

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