1EM6
HUMAN LIVER GLYCOGEN PHOSPHORYLASE A COMPLEXED WITH GLCNAC AND CP-526,423
Summary for 1EM6
Entry DOI | 10.2210/pdb1em6/pdb |
Descriptor | LIVER GLYCOGEN PHOSPHORYLASE, N-acetyl-beta-D-glucopyranosylamine, BIS[5-CHLORO-1H-INDOL-2-YL-CARBONYL-AMINOETHYL]-ETHYLENE GLYCOL, ... (6 entities in total) |
Functional Keywords | allosteric site, allosteric binding, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 196111.19 |
Authors | Rath, V.L.,Ammirati, M.,Danley, D.E.,Ekstrom, J.L.,Hynes, T.R.,Olson, T.V.,Hoover, D.J. (deposition date: 2000-03-16, release date: 2000-11-01, Last modification date: 2020-07-29) |
Primary citation | Rath, V.L.,Ammirati, M.,Danley, D.E.,Ekstrom, J.L.,Gibbs, E.M.,Hynes, T.R.,Mathiowetz, A.M.,McPherson, R.K.,Olson, T.V.,Treadway, J.L.,Hoover, D.J. Human liver glycogen phosphorylase inhibitors bind at a new allosteric site. Chem.Biol., 7:677-682, 2000 Cited by PubMed: 10980448DOI: 10.1016/S1074-5521(00)00004-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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