1EAW
Crystal structure of the MTSP1 (matriptase)-BPTI (aprotinin) complex
Summary for 1EAW
Entry DOI | 10.2210/pdb1eaw/pdb |
Related | 1EAX |
Descriptor | SUPPRESSOR OF TUMORIGENICITY 14, PANCREATIC TRYPSIN INHIBITOR (3 entities in total) |
Functional Keywords | hydrolase/inhibitor, complex (serine protease inhibitor), serine proteinase, matrix degradation, inhibitor, glycoprote hydrolase, hydrolase-inhibitor complex |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Membrane ; Single-pass type II membrane protein : Q9Y5Y6 Secreted: P00974 |
Total number of polymer chains | 4 |
Total formula weight | 65982.65 |
Authors | Friedrich, R.,Bode, W. (deposition date: 2001-07-17, release date: 2002-01-28, Last modification date: 2023-12-13) |
Primary citation | Friedrich, R.,Fuentes-Prior, P.,Ong, E.,Coombs, G.,Hunter, M.,Oehler, R.,Pierson, D.,Gonzalez, R.,Huber, R.,Bode, W.,Madison, E.L. Catalytic Domain Structures of Mt-Sp1/Matriptase, a Matrix-Degrading Transmembrane Serine Proteinase. J.Biol.Chem., 277:2160-, 2002 Cited by PubMed: 11696548DOI: 10.1074/JBC.M109830200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.93 Å) |
Structure validation
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