1DX5

Crystal structure of the thrombin-thrombomodulin complex

Summary for 1DX5

Entry DOI	10.2210/pdb1dx5/pdb
Related PRD ID	PRD_000288
Descriptor	Thrombin light chain, Thrombomodulin, Thrombin heavy chain, ... (9 entities in total)
Functional Keywords	serine proteinase, egf-like domains, anticoagulant complex, antifibrinolytic complex, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Homo sapiens (Human) More
Total number of polymer chains	12
Total formula weight	194112.57
Authors	Fuentes-Prior, P.,Iwanaga, Y.,Huber, R.,Pagila, R.,Rumennik, G.,Seto, M.,Morser, J.,Light, D.R.,Bode, W. (deposition date: 1999-12-20, release date: 2000-04-10, Last modification date: 2020-07-29)
Primary citation	Fuentes-Prior, P.,Iwanaga, Y.,Huber, R.,Pagila, R.,Rumennik, G.,Seto, M.,Morser, J.,Light, D.R.,Bode, W. Structural Basis for the Anticoagulant Activity of the Thrombin-Thrombomodulin Complex Nature, 404:518-, 2000 Cited by PubMed: 10761923 DOI: 10.1038/35006683 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation