1DWD
CRYSTALLOGRAPHIC ANALYSIS AT 3.0-ANGSTROMS RESOLUTION OF THE BINDING TO HUMAN THROMBIN OF FOUR ACTIVE SITE-DIRECTED INHIBITORS
Summary for 1DWD
Entry DOI | 10.2210/pdb1dwd/pdb |
Related | 1DWB 1DWC 1DWE |
Related PRD ID | PRD_000451 |
Descriptor | ALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), HIRUDIN IIIA, ... (5 entities in total) |
Functional Keywords | serine proteinase, hydrolase-hyrolase inhibitor complex, hydrolase/hyrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted, extracellular space: P00734 P00734 Secreted: P28508 |
Total number of polymer chains | 3 |
Total formula weight | 35809.85 |
Authors | Banner, D.W.,Hadvary, P. (deposition date: 1992-08-19, release date: 1994-01-31, Last modification date: 2024-06-05) |
Primary citation | Banner, D.W.,Hadvary, P. Crystallographic analysis at 3.0-A resolution of the binding to human thrombin of four active site-directed inhibitors. J.Biol.Chem., 266:20085-20093, 1991 Cited by PubMed: 1939071PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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