1DQD
CRYSTAL STRUCTURE OF FAB HGR-2 F6, A COMPETITIVE ANTAGONIST OF THE GLUCAGON RECEPTOR
Summary for 1DQD
Entry DOI | 10.2210/pdb1dqd/pdb |
Descriptor | FAB HGR-2 F6 (3 entities in total) |
Functional Keywords | glucagon receptor, monoclonal antibody, fab, receptor antagonist, typical immunoglobulin fold, light chain, heavy chain, antigen binding site, complementarity-determining regions, immune system |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 2 |
Total formula weight | 47846.04 |
Authors | Wright, L.M.,Brzozowski, A.M.,Hubbard, R.E.,Pike, A.C.W.,Roberts, S.M.,Skovgaard, R.N.,Svendsen, I.,Vissing, H.,Bywater, R.P. (deposition date: 2000-01-04, release date: 2000-05-10, Last modification date: 2011-07-13) |
Primary citation | Wright, L.M.,Brzozowski, A.M.,Hubbard, R.E.,Pike, A.C.,Roberts, S.M.,Skovgaard, R.N.,Svendsen, I.,Vissing, H.,Bywater, R.P. Structure of Fab hGR-2 F6, a competitive antagonist of the glucagon receptor. Acta Crystallogr.,Sect.D, 56:573-580, 2000 Cited by PubMed: 10771426DOI: 10.1107/S090744490000233X PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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