1DD7

MURINE INDUCIBLE NITRIC OXIDE SYNTHASE OXYGENASE DOMAIN (DELTA 114) (N-[(1,3-BENZODIOXOL-5-YL)METHYL]-1-[2-(1H-IMIDAZOL-1-YL)PYRIMIDIN-4-YL]-4-(METHOXYCARBONYL)-PIPERAZINE-2-ACETAMIDE COMPLEX

Summary for 1DD7

Entry DOI	10.2210/pdb1dd7/pdb
Related	1NOC 1NOD 1NOS 1NSI 2NOS
Descriptor	INDUCIBLE NITRIC OXIDE SYNTHASE, SULFITE ION, PROTOPORPHYRIN IX CONTAINING FE, ... (5 entities in total)
Functional Keywords	nitric oxide, l-arginine monooxygenase, heme, dimerization, inhibitor, nos, oxidoreductase
Biological source	Mus musculus (house mouse)
Total number of polymer chains	1
Total formula weight	46446.42
Authors	Adler, M.,Whitlow, M. (deposition date: 1999-11-08, release date: 2000-03-29, Last modification date: 2022-12-21)
Primary citation	McMillan, K.,Adler, M.,Auld, D.S.,Baldwin, J.J.,Blasko, E.,Browne, L.J.,Chelsky, D.,Davey, D.,Dolle, R.E.,Eagen, K.A.,Erickson, S.,Feldman, R.I.,Glaser, C.B.,Mallari, C.,Morrissey, M.M.,Ohlmeyer, M.H.,Pan, G.,Parkinson, J.F.,Phillips, G.B.,Polokoff, M.A.,Sigal, N.H.,Vergona, R.,Whitlow, M.,Young, T.A.,Devlin, J.J. Allosteric inhibitors of inducible nitric oxide synthase dimerization discovered via combinatorial chemistry. Proc.Natl.Acad.Sci.USA, 97:1506-1511, 2000 Cited by PubMed: 10677491 DOI: 10.1073/pnas.97.4.1506 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation