1D85
STRUCTURAL CONSEQUENCES OF A CARCINOGENIC ALKYLATION LESION ON DNA: EFFECT OF O6-ETHYL-GUANINE ON THE MOLECULAR STRUCTURE OF D(CGC[E6G]AATTCGCG)-NETROPSIN COMPLEX
Summary for 1D85
Entry DOI | 10.2210/pdb1d85/pdb |
Descriptor | DNA (5'-D(*CP*GP*CP*(G36)P*AP*AP*TP*TP*CP*GP*CP*G)-3'), NETROPSIN (3 entities in total) |
Functional Keywords | b-dna, double helix, complexed with drug, modified, dna |
Total number of polymer chains | 2 |
Total formula weight | 7813.35 |
Authors | Sriram, M.,Van Der Marel, G.A.,Roelen, H.L.P.F.,Van Boom, J.H.,Wang, A.H.-J. (deposition date: 1992-08-24, release date: 1993-07-15, Last modification date: 2024-02-07) |
Primary citation | Sriram, M.,van der Marel, G.A.,Roelen, H.L.,van Boom, J.H.,Wang, A.H. Structural consequences of a carcinogenic alkylation lesion on DNA: effect of O6-ethylguanine on the molecular structure of the d(CGC[e6G]AATTCGCG)-netropsin complex. Biochemistry, 31:11823-11834, 1992 Cited by PubMed: 1332773DOI: 10.1021/bi00162a022 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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