1D6W
STRUCTURE OF THROMBIN COMPLEXED WITH SELECTIVE NON-ELECTROPHILIC INHIBITORS HAVING CYCLOHEXYL MOIETIES AT P1
Summary for 1D6W
Entry DOI | 10.2210/pdb1d6w/pdb |
Descriptor | THROMBIN, DECAPEPTIDE INHIBITOR, SODIUM ION, ... (5 entities in total) |
Functional Keywords | hydrolase, thrombin, thrombin inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted, extracellular space: P00734 Secreted: P28511 |
Total number of polymer chains | 2 |
Total formula weight | 35030.97 |
Authors | Mochalkin, I.,Tulinsky, A. (deposition date: 1999-10-15, release date: 2000-10-25, Last modification date: 2017-10-04) |
Primary citation | Krishnan, R.,Mochalkin, I.,Arni, R.,Tulinsky, A. Structure of thrombin complexed with selective non-electrophilic inhibitors having cyclohexyl moieties at P1. Acta Crystallogr.,Sect.D, 56:294-303, 2000 Cited by PubMed: 10713516DOI: 10.1107/S0907444900000068 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
Download full validation report