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1D3G

HUMAN DIHYDROOROTATE DEHYDROGENASE COMPLEXED WITH BREQUINAR ANALOG

Summary for 1D3G

Related1D3H 
DescriptorDIHYDROOROTATE DEHYDROGENASE (1.3.3.1)
Functional KeywordsPROTEIN-ANTIPROLIFERATIVE AGENT COMPLEX, OXIDOREDUCTASE,OXIDOREDUCTASE
Biological sourceHomo sapiens (human)
Cellular locationMitochondrion inner membrane; Single-pass membrane protein Q02127 
Total number of polymer chains1
Total molecular weight41183.22
Authors
Liu, S.,Neidhardt, E.A.,Grossman, T.H.,Ocain, T.,Clardy, J. (deposition date: 1999-09-29, release date: 2000-09-13, modification date: 2009-02-24)
Primary citation
Liu, S.,Neidhardt, E.A.,Grossman, T.H.,Ocain, T.,Clardy, J.
Structures of human dihydroorotate dehydrogenase in complex with antiproliferative agents.
Structure Fold.Des., 8:25-33, 2000
PubMed: 10673429
DOI: 10.1016/S0969-2126(00)00077-0
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.6 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.18800.3%1.4%5.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolutionDownload full validation report

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105097
entries available on 2014-12-17
00:00 UTC / 09:00 JST