1D3G

HUMAN DIHYDROOROTATE DEHYDROGENASE COMPLEXED WITH BREQUINAR ANALOG

Summary for 1D3G

Related1D3H
DescriptorDIHYDROOROTATE DEHYDROGENASE (1.3.3.1)
Functional Keywordsprotein-antiproliferative agent complex, oxidoreductase
Biological sourceHomo sapiens (human)
Cellular locationMitochondrion inner membrane; Single-pass membrane protein Q02127
Total number of polymer chains1
Total molecular weight41183.22
Authors
Liu, S.,Neidhardt, E.A.,Grossman, T.H.,Ocain, T.,Clardy, J. (deposition date: 1999-09-29, release date: 2000-09-13, modification date: 2009-02-24)
Primary citation
Liu, S.,Neidhardt, E.A.,Grossman, T.H.,Ocain, T.,Clardy, J.
Structures of human dihydroorotate dehydrogenase in complex with antiproliferative agents.
Structure Fold.Des., 8:25-33, 2000
PubMed: 10673429
DOI: 10.1016/S0969-2126(00)00077-0
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.6 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.18450.3%1.4%6.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 1d3g
no rotation
Molmil generated image of 1d3g
rotated about x axis by 90°
Molmil generated image of 1d3g
rotated about y axis by 90°
Copyright © 2013-2016 Protein Data Bank Japan