1CQN
PROTEIN AGGREGATION AND ALZHEIMER'S DISEASE: CRYSTALLOGRAPHIC ANALYSIS OF THE PHENOMENON. ENGINEERED VERSION OF THE RIBOSOMAL PROTEIN S6 USED AS A STABLE SCAFFOLD TO STUDY OLIGOMERIZATION.
Summary for 1CQN
Entry DOI | 10.2210/pdb1cqn/pdb |
Related | 1CQM 1QJH |
Descriptor | RIBOSOMAL PROTEIN S6 (2 entities in total) |
Functional Keywords | alzheimer disease, ribosomal protein s6, oligomerization, ribosomal protein |
Biological source | Thermus thermophilus |
Total number of polymer chains | 2 |
Total formula weight | 23829.52 |
Authors | Kristensen, O.,Otzen, D.E.,Oliveberg, M. (deposition date: 1999-08-08, release date: 2000-09-08, Last modification date: 2024-02-07) |
Primary citation | Otzen, D.E.,Kristensen, O.,Oliveberg, M. Designed protein tetramer zipped together with a hydrophobic Alzheimer homology: a structural clue to amyloid assembly. Proc.Natl.Acad.Sci.USA, 97:9907-9912, 2000 Cited by PubMed: 10944185DOI: 10.1073/pnas.160086297 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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