1CL2
CYSTATHIONINE BETA-LYASE (CBL) FROM ESCHERICHIA COLI IN COMPLEX WITH AMINOETHOXYVINYLGLYCINE
Summary for 1CL2
Entry DOI | 10.2210/pdb1cl2/pdb |
Descriptor | CYSTATHIONINE BETA-LYASE, (2E,3E)-4-(2-aminoethoxy)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)imino]but-3-enoic acid (3 entities in total) |
Functional Keywords | methionine biosynthesis, plp-dependent enzymes, c-s beta lyase, aminoethoxyvinylglycine, slow-binding inhibition |
Biological source | Escherichia coli |
Cellular location | Cytoplasm: P06721 |
Total number of polymer chains | 2 |
Total formula weight | 87301.14 |
Authors | Clausen, T.,Huber, R.,Messerschmidt, A. (deposition date: 1997-09-04, release date: 1998-09-09, Last modification date: 2024-02-07) |
Primary citation | Clausen, T.,Huber, R.,Messerschmidt, A.,Pohlenz, H.D.,Laber, B. Slow-binding inhibition of Escherichia coli cystathionine beta-lyase by L-aminoethoxyvinylglycine: a kinetic and X-ray study. Biochemistry, 36:12633-12643, 1997 Cited by PubMed: 9376370DOI: 10.1021/bi970630m PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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