1C3R
CRYSTAL STRUCTURE OF AN HDAC HOMOLOG COMPLEXED WITH TRICHOSTATIN A
Summary for 1C3R
Entry DOI | 10.2210/pdb1c3r/pdb |
Related | 1C3P 1C3S |
Descriptor | HDLP (HISTONE DEACETYLASE-LIKE PROTEIN), ZINC ION, TRICHOSTATIN A, ... (4 entities in total) |
Functional Keywords | alpha/beta fold, hydroxamic acid, charge-relay system, penta-coordinated zinc, lyase |
Biological source | Aquifex aeolicus |
Total number of polymer chains | 2 |
Total formula weight | 86138.84 |
Authors | Finnin, M.S.,Donigian, J.R.,Pavletich, N.P. (deposition date: 1999-07-28, release date: 1999-09-15, Last modification date: 2024-02-07) |
Primary citation | Finnin, M.S.,Donigian, J.R.,Cohen, A.,Richon, V.M.,Rifkind, R.A.,Marks, P.A.,Breslow, R.,Pavletich, N.P. Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors. Nature, 401:188-193, 1999 Cited by PubMed: 10490031DOI: 10.1038/43710 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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