1BUL

6ALPHA-(HYDROXYPROPYL)PENICILLANATE ACYLATED ON NMC-A BETA-LACTAMASE FROM ENTEROBACTER CLOACAE

Summary for 1BUL

• Entry DOI: 10.2210/pdb1bul/pdb
• Descriptor: NMC-A BETA-LACTAMASE, 2-(1-CARBOXY-2-HYDROXY-2-METHYL-PROPYL)-5,5-DIMETHYL-THIAZOLIDINE-4-CARBOXYLIC ACID, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (4 entities in total)
• Functional Keywords: hydrolase, antibiotic resistance, class a carbapenemase
• Biological source: Enterobacter cloacae
• Total number of polymer chains: 1
• Total formula weight: 30000.64

Authors

Mourey, L.,Swaren, P.,Miyashita, K.,Bulychev, A.,Mobashery, S.,Samama, J.P. (deposition date: 1998-09-04, release date: 1998-12-30, Last modification date: 2024-04-03)

• Primary citation: Mourey, L.,Swaren, P.,Miyashita, K.,Bulychev, A.,Mobashery, S.,Samama, J.P.; Inhibition of the Nmc-A B-Lactamase by a Penicillanic Acid Derivative, and the Structural Bases for the Increase in Substrate Profile of This Antibiotic Resistance Enzyme; J.Am.Chem.Soc., 120:9382-9383, 1998

Experimental method

X-RAY DIFFRACTION (1.89 Å)