1BFC
BASIC FIBROBLAST GROWTH FACTOR COMPLEXED WITH HEPARIN HEXAMER FRAGMENT
Summary for 1BFC
Entry DOI | 10.2210/pdb1bfc/pdb |
Descriptor | BASIC FIBROBLAST GROWTH FACTOR, 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose (3 entities in total) |
Functional Keywords | growth factor, mitogen, vascularization, heparin-binding |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 18249.29 |
Authors | Faham, S.,Rees, D.C. (deposition date: 1995-12-12, release date: 1996-04-03, Last modification date: 2024-02-07) |
Primary citation | Faham, S.,Hileman, R.E.,Fromm, J.R.,Linhardt, R.J.,Rees, D.C. Heparin structure and interactions with basic fibroblast growth factor. Science, 271:1116-1120, 1996 Cited by PubMed: 8599088PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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