1B8Y
X-RAY STRUCTURE OF HUMAN STROMELYSIN CATALYTIC DOMAIN COMPLEXED WITH NON-PEPTIDE INHIBITORS: IMPLICATIONS FOR INHIBITOR SELECTIVITY
Summary for 1B8Y
Entry DOI | 10.2210/pdb1b8y/pdb |
Descriptor | PROTEIN (STROMELYSIN-1), ZINC ION, CALCIUM ION, ... (6 entities in total) |
Functional Keywords | hydrolase, matrix metalloproteinase-3, stromelysin-1 |
Biological source | Homo sapiens (human) |
Cellular location | Secreted, extracellular space, extracellular matrix : P08254 |
Total number of polymer chains | 1 |
Total formula weight | 19511.48 |
Authors | Pavlovsky, A.G.,Williams, M.G.,Ye, Q.-Z.,Ortwine, D.F.,Purchase II, C.F.,White, A.D.,Dhanaraj, V.,Roth, B.D.,Johnson, L.L.,Hupe, D.,Humblet, C.,Blundell, T.L. (deposition date: 1999-02-03, release date: 1999-08-31, Last modification date: 2023-12-27) |
Primary citation | Pavlovsky, A.G.,Williams, M.G.,Ye, Q.Z.,Ortwine, D.F.,Purchase II, C.F.,White, A.D.,Dhanaraj, V.,Roth, B.D.,Johnson, L.L.,Hupe, D.,Humblet, C.,Blundell, T.L. X-ray structure of human stromelysin catalytic domain complexed with nonpeptide inhibitors: implications for inhibitor selectivity. Protein Sci., 8:1455-1462, 1999 Cited by PubMed: 10422833PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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