1B6J
HIV-1 PROTEASE COMPLEXED WITH MACROCYCLIC PEPTIDOMIMETIC INHIBITOR 1
Summary for 1B6J
Entry DOI | 10.2210/pdb1b6j/pdb |
Related | 1B6K 1B6L 1B6M 1B6N 1B6O 1B6P |
Related PRD ID | PRD_000407 |
Descriptor | RETROPEPSIN, CYCLIC PEPTIDE INHIBITOR, SULFATE ION, ... (4 entities in total) |
Functional Keywords | complex (acid proteinase-peptide), hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Human immunodeficiency virus 1 |
Cellular location | Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P03369 |
Total number of polymer chains | 3 |
Total formula weight | 22585.19 |
Authors | Martin, J.L.,Begun, J.,Schindeler, A.,Wickramasinghe, W.A.,Alewood, D.,Alewood, P.F.,Bergman, D.A.,Brinkworth, R.I.,Abbenante, G.,March, D.R.,Reid, R.C.,Fairlie, D.P. (deposition date: 1999-01-17, release date: 2000-01-07, Last modification date: 2023-11-15) |
Primary citation | Martin, J.L.,Begun, J.,Schindeler, A.,Wickramasinghe, W.A.,Alewood, D.,Alewood, P.F.,Bergman, D.A.,Brinkworth, R.I.,Abbenante, G.,March, D.R.,Reid, R.C.,Fairlie, D.P. Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease. Biochemistry, 38:7978-7988, 1999 Cited by PubMed: 10387041DOI: 10.1021/bi990174x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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