1A6Z
HFE (HUMAN) HEMOCHROMATOSIS PROTEIN
Summary for 1A6Z
Entry DOI | 10.2210/pdb1a6z/pdb |
Descriptor | HFE, BETA-2-MICROGLOBULIN (3 entities in total) |
Functional Keywords | hfe, hereditary hemochromatosis, mhc class i, mhc class i complex |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane ; Single-pass type I membrane protein : Q30201 Secreted . Note=(Microbial infection) In the presence of M: P61769 |
Total number of polymer chains | 4 |
Total formula weight | 88175.19 |
Authors | Lebron, J.A.,Bennett, M.J.,Vaughn, D.E.,Chirino, A.J.,Snow, P.M.,Mintier, G.A.,Feder, J.N.,Bjorkman, P.J. (deposition date: 1998-03-04, release date: 1999-03-23, Last modification date: 2023-08-02) |
Primary citation | Lebron, J.A.,Bennett, M.J.,Vaughn, D.E.,Chirino, A.J.,Snow, P.M.,Mintier, G.A.,Feder, J.N.,Bjorkman, P.J. Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor. Cell(Cambridge,Mass.), 93:111-123, 1998 Cited by PubMed: 9546397DOI: 10.1016/S0092-8674(00)81151-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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