1A42
HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH BRINZOLAMIDE
Summary for 1A42
Entry DOI | 10.2210/pdb1a42/pdb |
Descriptor | CARBONIC ANHYDRASE II, MERCURY (II) ION, ZINC ION, ... (5 entities in total) |
Functional Keywords | lyase, zinc, inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P00918 |
Total number of polymer chains | 1 |
Total formula weight | 29807.37 |
Authors | Boriack-Sjodin, P.A.,Christianson, D.W. (deposition date: 1998-02-10, release date: 1999-03-23, Last modification date: 2024-04-03) |
Primary citation | Stams, T.,Chen, Y.,Boriack-Sjodin, P.A.,Hurt, J.D.,Liao, J.,May, J.A.,Dean, T.,Laipis, P.,Silverman, D.N.,Christianson, D.W. Structures of murine carbonic anhydrase IV and human carbonic anhydrase II complexed with brinzolamide: molecular basis of isozyme-drug discrimination. Protein Sci., 7:556-563, 1998 Cited by PubMed: 9541386PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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